publications
Article
Retinol and Alpha-tocopherol in the Colostrum of Lactating Tunisian Women Delivering Prematurely: Associations with Maternal Characteristics |
Fares Samira, Sethom Mohamed Marouen , FEKI Moncef, KAABACHI Naziha, 2017 |
Pediatrics and Neonatology, 10.1016, 2015.06.003, 1-7, Janvier 2017 |
Résumé
This study aims to assess vitamin A and E concentrations in the premature colostrum
of lactating Tunisian women and to identify maternal characteristics that may affect
these concentrations.
Methods: Human colostrum was obtained from 105 mothers who gave birth prematurely in the
Centre for Maternity and Neonatology of Tunis (Tunisia). Retinol and alpha-tocopherol were
analyzed in the colostrum and in plasma by high-performance liquid chromatography.
Results: Retinol and alpha-tocopherol concentrations were 57.5 50.1 mg/dL and
1222 772 mg/dL in the colostrum, respectively, and 51.7 20.0 mg/dL and 1351 772 mg/
dL in plasma, respectively. Concentrations of each vitamin in the colostrum were positively
correlated with their respective concentrations in plasma (r Z 0.415, p Z 0.001 for retinol
and r Z 0.392, p Z 0.003 for alpha-tocopherol). In multivariate analysis, colostrum vitamin
A was associated with plasma vitamin A and preeclampsia, while colostrum vitamin E was associated
with plasma vitamin E, gestational age, and preeclampsia.
Conclusion: In Tunisian women, colostrum vitamin A and E levels are close to the average
values reported in the literature. The levels are too low to cover the needs of very low birth
weight (VLBW) infants, particularly in women with plasma vitamin deficiencies, preeclampsia,
or very premature delivery. Given the undeniable beneficial effects of human colostrum,
This study aims to assess vitamin A and E concentrations in the premature colostrumof lactating Tunisian women and to identify maternal characteristics that may affectthese concentrations.Methods: Human colostrum was obtained from 105 mothers who gave birth prematurely in theCentre for Maternity and Neonatology of Tunis (Tunisia). Retinol and alpha-tocopherol wereanalyzed in the colostrum and in plasma by high-performance liquid chromatography.Results: Retinol and al
